Paper Title :An Ultra-Sensitive Detection of cxcr4 in Human Liver Cancer Cells on Photonic Crystal Surface
Author :Naseerullah Khan, Hua Heand Fang Huang
Article Citation :Naseerullah Khan ,Hua Heand Fang Huang ,
(2018 ) " An Ultra-Sensitive Detection of cxcr4 in Human Liver Cancer Cells on Photonic Crystal Surface " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 26-29,
Volume-6, Issue-1, Spl. Iss-2
Abstract : Amplification of fluorescence intensity is of important role to the development of chemical and biochemical
imaging and sensing. Here, we report the fluorescence enhancement from Cyanine-5 (Cy5) organic dye on the surface of
three-dimensional photonic crystal. The enhancement is due to the overlapping between emission wavelength of organic dyes
and photonic stop bands of photonic crystals. The fabricated three dimentional (3D) photonic crystals surface enhanced the
fluorescence intensity by a factor up to 390- fold compared with Cy5 on an unpatterned glass surface. This platform is
accessible to a wide range of users in an ordinary lab only by drop drying of poly styrene-co-N-isopropyl acrylamide
p(St-co-NIPAM) spheres on the glass substrate. We applied the self-assembled colloidal photonic crystals (PhCs) platform for
detecting CXCR4 in human liver cancer (HePG2) cells through sandwich immunoassay format.
Index Terms- Cy5, Cy3 Organic dye, CXCR4,Fluorescence enhancement, photonic crystals
Type : Research paper
Published : Volume-6, Issue-1, Spl. Iss-2
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-11699
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Copyright: © Institute of Research and Journals
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Published on 2018-05-15 |
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