Paper Title :Synthesis and Biological Evaluation of Schiff Base Derivatives of Furfural based Heterocyclic Flavones
Author :Hari Babu Bollikolla, Bala Murali Krishna Khandapu
Article Citation :Hari Babu Bollikolla ,Bala Murali Krishna Khandapu ,
(2018 ) " Synthesis and Biological Evaluation of Schiff Base Derivatives of Furfural based Heterocyclic Flavones " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 42-43,
Volume-6, Issue-3, Spl. Iss-1
Abstract : Synthesized a total of twelve new furfural flavone Schiff base derivatives starting from commercially available
phloroglucinol. In the first stage the corresponding acetophenone key intermediate was synthesized from the starting material
and was condensed with furfural followed by cyclisation, and formylation. Finally, the formylated flavone was condensed with
various aromatic primary amines to obtain the desired Schiff base derivatives. All the synthesized furfural flavone Schiff base
derivatives were tested for their anticancer and antibacterial activities and the results were analysed in the light of their
structural activity.
Index Terms - Furfuralflavone, Aromatic Amines, Schiff Bases, Antibacterial Activity.
Type : Research paper
Published : Volume-6, Issue-3, Spl. Iss-1
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-13393
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Published on 2018-10-29 |
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