Paper Title :Citrullination of Adenosine Deaminase in Synovial Fluid at Septic Arthritis
Author :L.G. Karapetyan
Article Citation :L.G. Karapetyan ,
(2018 ) " Citrullination of Adenosine Deaminase in Synovial Fluid at Septic Arthritis " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 60-62,
Volume-6, Issue-3, Spl. Iss-2
Abstract : As result of posttranslational modification by peptidyl arginine deiminases, arginine residues in proteins
transform to citrulline. Abnormal modifications of citrullinated proteins are registeredat some severe human diseases, such
as Alzheimer’s and Parkinson’s diseases, rheumatoid arthritis (RA), etc. One of the most important discoveries in
rheumatology is the characterization of citrullinated auto-antigens. These antigens and the detection of anti-citrullinated
protein antibodies are major achievements in the diagnostics of arthritis. The present investigation showed that a smallmolecular
form of adenosine deaminase (SADA) in synovial fluid (SF) of septic arthritis (SA) is citrullinated.
Key words -Arthritis, citrullinated adenosine deaminase, septic arthritis, synovial fluid.
Type : Research paper
Published : Volume-6, Issue-3, Spl. Iss-2
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-13764
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Copyright: © Institute of Research and Journals
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Published on 2018-12-13 |
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